COMPOSITION
Ivermectin …………………………………………………………………… ....… .... …… .. 1.00 g
Clorsulon …………………………………………………………………………………… ..10,00g
Excipient q.s.p. ……… .. ……………………………………………………………… ....… 100 ml
PHARMACEUTICAL PROPERTIES
Ivermectin is an antiparasitic of the avermectin family with great activity
both internal and external parasites of domestic animals (endectocide).
Ivermectin acts on nematodes and arthropods through gamma acid
amino-butyric acid (GABA). It causes its release from the presynaptic membrane and
potentiates its binding to receptors located on the postsynaptic membrane. GABA is a
neurotransmitter involved in the transmission of inhibitory messages between the inter-neuron
and the motor neuron in nematodes, and between the nerve fiber and muscle cell in
arthropods.
At recommended doses, ivermectin is very well tolerated in both adults and patients.
young and can be used at all stages of gestation.
Ivermectin is not active against fluke and tapeworms.
Clorsulone inhibits enzymes of the glycolytic system of Fasciola hepatica (3-
phosphoglycerate kinase and phosphoglyceromutase). This enzyme inhibition blocks the pathway
Embden-Myerhof glycolytic, the main energy source of Fasciola hepatica.
The combination of the two active ingredients further broadens the spectrum of the preparation.
TARGET SPECIES
Sheep, cattle
INDICATIONS
The treatment of gastrointestinal and pulmonary nematodoses, trematodoses,
external infestations due to lice and agents of scabies, ovine estrosis and hypodermosis
bovine
ADMINISTRATION AND DOSAGE
ATLAMEC-D is recommended exclusively by the subcutaneous route as a single dose of 1 ml of
solution / 50 kg bodyweight, corresponding to 0.2 mg of ivermectin and 2 mg of clorsulon per
kilogram of live weight.
CONTRAINDICATIONS AND INTERACTIONS
Do not use in dairy females when the milk or its derivatives are intended for
human consumption.
None if all recommendations are followed.
SIDE EFFECTS
If the general terms of use are followed, no adverse effects are observed after
treatment with Atlamec-D.
PRECAUTIONS FOR USE
Do not inject intravenously or intramuscularly.
Do not smoke or eat while using the product.
Keep out of the reach of children.
Avoid contact with skin or eyes.
Destroy the vial after use.
TIMEOUT
Meat and offal: 28 days
Milk: Do not use in dairy females when the milk or its derivatives are intended for
human consumption.
STORAGE CONDITIONS
Product stable for 2 years in the original packaging, protected from light and at a temperature
≤ 25 ° C.
Stability after opening: 4 weeks
PHARMACEUTICAL FORM AND PRESENTATION:
50 and 100 ml bottle
